PERANAN ZINC DAN RETINOL TERHADAP AKTIFITAS SELULER LMFOSIT T DAN IGG PADA ANAK TUBERKULOSIS DAN NON TUBERKULOSIS

Abstract

ABSTRACT. Zinc plays an important role in the human immune system, from the skin barrier up to the the regulation system in the lympocytes. Zinc is required to the normal development of non-specific immunity system which is mediated by netropyhil, the natural killer cells and the specific development of immune itself called the growth and development function of T-lympocytes. Vitamin A has an affection on the humans’ immune body function which is certainty specific unknown mechanism yet. Basically, Vitamin A plays on the forming process of immune system. This study used an observational analytic. The model used in this study was comparision study with applying cross sectional design. The sampling technique of this study was simple random sampling technique. This study was conducted at RSUD Sidoarjo by taking the sample of 11 tubercular children and 11 non-tubercular children. Based on the study above, this was obtained that the average level of zinc with the significance value was 0.000. The significance value was less than α=0.000. The level of T-limphocytes was obtained t-amount -7.481 and the significance value was 0.000. meanwhile, the significance value was less than α=0.05, the level of retinol was obtained t-amount 4.013 and the significance level was 0.002. then, the level of significance was less than α=0.05, the level of IgG was obtained t-amount 3.506 with the level of significance was 0.005. The level of significance was less than α=0.05.  Key words: Zinc Serum, Retinol, T-lyphocytes, Imunoglobulin G, Tubercolosis