Journal of Kendedes Health Science

Budaya Pascasalin Di Kabupaten Gianyar Bali Pada Periode Laktasi : Kajian Kearifan Lokal Dari Perspektif Maturasi Barier Mukosa Saluran Cerna Neonatus

Kadek Agus Kurniawan — 2022-12-06

The success of lactation is an important part of supporting
the quality of infant development, especially in the colostrum
phase, due to the higher levels of Immunoglobulin A (IgA)
in the colostrum phase compared to the mature milk period.
Herbal applications for breastfeeding mothers include the
consumption of Sauropus Androginus empirically proven
to increase breast milk production. This study is designed to
present an overview of postpartum culture, especially nursing
mother care for the community in Gianyar Regency, Bali.
Methods: 81 postpartum mothers in 2017-2018 were enrolled
in this study. Screening and interviews regarding efforts to
increase milk production during the postpartum period were
conducted by trained enumerators. Participants are residents
of the Supervision Program for the First 1000 Days of Life,
Faculty of Medicine, University of Warmadewa, Bali, which have been followed during pregnancy, childbirth and the
postpartum period.
Results: Consumption of vitamins and Sauropus Androgynus
are the methods that are widely used by postpartum mothers
to increase milk production during breastfeeding. Twentyeight point four of 81 postpartum mothers reported that they
had consumed S. Androgynus leaf decoction since the first day
postpartum and 14.8% consumed Asifit.

Conclusion: The people of Gianyar Bali Regency still
honour and practice post-partum culture through
consumption of boiled S. Androgynus leaves to increase
breast milk production. The bioactive component of S.
Androgynus as an anti-inflammatory and anti-oxidant may
have a potential effect on reducing IgA levels in breast
milk. It is necessary to prove the effect of consuming S.
Androgynus leaf decoction based on laboratory tests as an
effort to support the maturation of the gastrointestinal tract
system of neonates during the lactation period.
Keywords: Postpartum Culture in Bali, IgA, Breastfeeding,
Sauropus Androgynus.

Kajian Tingkat Kecemasan Penderita Astma di Puskesmas Dau Sebagai Salah Satu Kontributor Kekambuhan Astma

Wahidyanti Rahayu Hastutiningtyas — 2022-09-27

Asthma is a chronic inflammatory event in the airways
caused by bronchial hyperactivity to certain stimuli and is
characterized by the main symptom of shortness of breath.
People with asthma will experience anxiety caused by a
person’s life being disrupted, and mental stress, behavior
changes, social interactions are disrupted, and appetite is
reduced. The purpose of the study was to describe the level
of anxiety in asthmatics at the Dau Health Center, Malang
Regency. The research design used a cross sectional
approach. The study population was 42 asthma patients
who routinely controlled to the health center and the study
sample was 38 respondents using purposive sampling.
The data collection technique used an instrument in the
form of an anxiety level questionnaire (HRS-A/Hamilton
Rating Scale for Anxiety/). The results showed that most of
the 25 (65.8%) respondents experienced moderate levels
of anxiety, 10 (26.3%) experienced mild anxiety and 3
(7.9%) experienced severe anxiety in asthmatics. Future
researchers are expected to examine the factors that cause
anxiety, namely marital status, alcohol drinking habits and
family economic status.

Karakterisasi Depresi dari Perspektif Faktor Demografi dan Faktor Psikososial Ibu Postpartum di Surakarta

Siti Kholifah — 2022-09-27

Postpartum depression is a psychological disorder after
partum that is characterized by a feeling of sadness, fear,
anxiety, loneliness, suspicion, worthless and loss of hope. The
incidence rate of postpartum depression in Indonesia varies
from 50-70%. This research aims to illustrate the profile of
the demographic and psychosocial mother who experienced
postpartum depression in Surakarta. Research design is
descriptive. The samples of this study were mother who
experienced postpartum depression selected in 25 primary
health care using purposive sampling method with a total
of 66 respondents. The instrument used for measurement
is Edinburg Posnatal Depression Scale (EPDS). Results
showed that the average score of postpartum depression
was 11.71. Demographic profiles were the average age
of 28.26 (early adulthood category), balanced between
primipara and multipara, almost balanced between income
of < 1.5 million and ≥ 1.5 million per month, more common
in mothers with cesarean section delivery (74.2%) and low
education levels (92.4%). Psychosocial profiles were mother
with no previous history of stress, had harmonious marital
relationship, and almost entirely gained considerable
support from her family. Postpartum depression is more
common in mothers with cesarean section delivery and low
education levels. It is hoped that Primary Health Care can
carry out prevention efforts through screening based on
characteristics that contribute to postpartum depression

Penerapan Pola Asuh Permisif Meningkatkan Risiko Perilaku Bullying Remaja

Lembah Andriani — 2022-09-27

Bullying in childhood has detrimental effects on the mental
and social health of victims. Prevention of bullying is
important for achieving the Sustainable Development Goals,
with interventions on the etiology of bullying behavior in the
family. Parenting is one of the determinants of the formation
of child bullying behavior. This study aims to explore the
types of parenting styles that contribute to shaping adolescent
bullying behavior. This study involved 45 junior high school
students aged 13-14 years. Parenting patterns were validated
through students’ perspectives, while bullying behavior was
validated on students through several question items for selfassessment. Logistic regression analysis was carried out to
evaluate the dominant parenting styles that shape bullying
behavior in adolescents. Results: Identified bullying behavior
in adolescents included: hitting, bullying, beating, being rude,
speaking harshly, laughing at, insulting, threatening, looking
cynical, publicly embarrassing, isolating, terrorizing, pouting
and bullying. The results of the logistic regression analysis
showed that the parenting style of parents who applied
dominant permissive parenting tended to increase the potential
for the formation of bullying behavior in adolescents, which
was significant with an OR value of 0.04 (p=0.003). Based on
this, parents make a major contribution to preventing the rise
of adolescent bullying behavior by improving the quality of
communication and attention. This will encourage adolescent
understanding to be able to express emotions in the form of
more positive behavior.

Pengembangan Eksplorasi Determinan Respons Neoajuvan Kemoterapi Pasien Kanker Payudara Stadium Lanjut Lokal Berbasis Kuantifikasi Penanda Penekan Tumor

M. Bachtiar Budianto — 2022-09-27

The management of locally advanced breast cancer is still
an issue and challenge for every oncologist, including low
patient survival rates, high recurrences and unpredictable
chemotherapy responses. Aggressive behavior of cancer
cells is a determinant of poor therapeutic outcomes,
predominantly due to inhibition of tumor suppressor
p53 activity. This study aims to examine the response
of neoadjuvant chemotherapy based on p53 expression
in cancer tissue prior to administration of neoadjuvant
chemotherapy. At least 80 patients with locally advanced
breast cancer who will receive neoadjuvant chemotherapy
regimens of taxane or anthracycline types were included
in this retrospective cohort study. The results of cancer
tissue biopsies before chemotherapy were isolated for the
process of p53 staining using the immunohistochemical
method, followed by monitoring the response after giving
neoadjuvant chemotherapy for 3 cycles with an interval of
4 weeks each administration. Chemotherapy response was
based on RECIST 1.1 criteria by validating changes in tumor
volume before and after administration of neoadjuvant
chemotherapy. The results of this study indicated that p53
expression in locally advanced breast cancer tissue did not
affect differences in response to neoadjuvant chemotherapy
(p=0,6,21), p53 expression significantly increased
the positive response after administration of taxanebased chemotherapy better than anthracycline-based
chemotherapy ( OR 4.64;p=0.036). Based on these findings,

it can be concluded that the presence of p53 contributes to
the efficacy of neoadjuvant chemotherapy regimens but
cannot be used as a clinical predictor of response. It is still
necessary to study the mechanism of the role of p53 in the
drug efflux mechanism pathway which increases the risk of
a negative chemotherapy response.